Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364792 | 0.70 | GAA (0.46) | MEN1KMT2ATP53PTPN1NPC1 | |
| SCHEMBL429187 | 0.68 | PTPN1 (0.48) | MEN1KMT2ANAMPTMDM4TP53 | |
| SCHEMBL11128707 | 0.68 | MEN1 (0.56) | MEN1KMT2AMDM4TP53JAK2 | |
| SCHEMBL2730773 | 0.68 | PIM1 (0.72) | MEN1KMT2ANAMPTJAK2TYK2 | |
| SCHEMBL18293133 | 0.67 | MEN1 (0.55) | MEN1KMT2ANAMPTTP53JAK2 | |
| SCHEMBL11831465 | 0.66 | MEN1 (0.64) | MEN1KMT2ATP53JAK2TYK2 | |
| SCHEMBL3299661 | 0.66 | ADORA1 (0.70) | MEN1KMT2AJAK2TYK2BCAT2 | |
| SCHEMBL2801723 | 0.66 | KMT2A (0.54) | MEN1KMT2AMDM4TP53JAK2 | |
| SCHEMBL27663452 | 0.66 | HTT (0.55) | MEN1KMT2ATP53MAPTNPC1 | |
| SCHEMBL696662 | 0.66 | KMT2A (0.58) | MEN1KMT2AJAK2TYK2BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |