SCHEMBL3299661

SCHEMBL3299661

O=C(Nc1nc(NC(=O)c2ccccc2)nc(NC(=O)c2ccccc2)n1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.70
L3MBTL1 Q9Y468 1/20 0.69
KMT2A Q03164 3/20 0.64
MEN1 O00255 2/20 0.64
ADORA3 P0DMS8 3/20 0.60
F2 P00734 2/20 0.59
F12 P00748 1/20 0.59
ADORA2A P29274 1/20 0.59
MAPK1 P28482 1/20 0.57
JAK2 O60674 1/20 0.57
TYK2 P29597 1/20 0.57
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
KCNK3 O14649 1/20 0.55
KCNK9 Q9NPC2 1/20 0.55
PTPN1 P18031 1/20 0.55
BCAT2 O15382 1/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623093 0.90 L3MBTL1 (0.64) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL9566583 0.90 ADORA1 (0.70) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL2623094 0.86 ADORA1 (0.60) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL9504179 0.86 ADORA1 (0.65) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL9564262 0.86 ADORA1 (0.60) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL2623097 0.86 L3MBTL1 (0.77) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL11166514 0.85 ADORA1 (0.63) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL6498848 0.83 ADORA1 (1.00) ADORA1ADORA3F2F12ADORA2A
SCHEMBL10083716 0.83 RHOA (0.56) ADORA1L3MBTL1KMT2AMEN1ADORA3
SCHEMBL18300318 0.83 L3MBTL1 (1.00) ADORA1L3MBTL1KMT2AMEN1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127142-B2 Low temperature injection molding of polyarylene sulfide compositions TICONA LLC (US) 2015-09-08 US claimed
US-9102792-B2 High performance polymer composition with improved flow properties TICONA LLC (US) 2015-08-11 US claimed
US-9080036-B2 Nucleating system for polyarylene sulfide compositions TICONA LLC (US) 2015-07-14 US claimed
US-9045685-B2 Cast molded parts formed from a liquid crystalline polymer TICONA LLC (US) 2015-06-02 US claimed
US-20140350156-A1 Low Temperature Injection Molding of Polyarylene Sulfide Compositions TICONA LLC (US) 2014-11-27 US claimed
US-8852730-B2 Melt-extruded substrate for use in thermoformed articles TICONA LLC (US) 2014-10-07 US claimed
US-20140242385-A1 Liquid Crystalline Polymer Fibers TICONA LLC (US) 2014-08-28 US claimed
US-20140243485-A1 High Performance Polymer Composition with Improved Flow Properties TICONA LLC (US) 2014-08-28 US claimed
US-8796392-B2 Low temperature injection molding of polyarylene sulfide compositions TICONA LLC (US) 2014-08-05 US claimed
US-8669341-B2 Solid-state polymerization of a liquid crystalline polymer TICONA LLC (US) 2014-03-11 US claimed
US-20130158212-A1 Low Temperature Injection Molding of Polyarylene Sulfide Compositions TICONA LLC (US) 2013-06-20 US claimed
US-20130155597-A1 Molded Part for a Portable Electronic Device TICONA LLC (US) 2013-06-20 US claimed
US-20130062558-A1 Cast Molded Parts Formed from a Liquid Crystalline Polymer TICONA LLC (US) 2013-03-14 US claimed
US-20130052447-A1 Liquid Crystalline Polymer Composition Containing a Fibrous Filler TICONA LLC (US) 2013-02-28 US claimed
US-20130052446-A1 Melt-Extruded Substrate for Use in Thermoformed Articles TICONA LLC (US) 2013-02-28 US claimed
US-20130053532-A1 Melt Polymerization of Low Melt Viscosity Liquid Crystalline Polymers TICONA LLC (US) 2013-02-28 US claimed
US-20130048908-A1 Heat-Resistant Liquid Crystalline Polymer Composition having a Low Melting Temperature TICONA LLC (US) 2013-02-28 US claimed
US-20130053533-A1 Solid-State Polymerization of a Liquid Crystalline Polymer TICONA LLC (US) 2013-02-28 US claimed
US-20130053531-A1 Method for Minimizing Process Disruptions During Formation of a Liquid Crystalline Polymer TICONA LLC (US) 2013-02-28 US claimed
US-20130048909-A1 High Flow Liquid Crystalline Polymer Composition TICONA LLC (US) 2013-02-28 US claimed