SCHEMBL6965475

SCHEMBL6965475

CC(=CCn1ccnc1)c1ccc2c(c1)CCCC2.CS(=O)(=O)Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
TBXAS1 P24557 7/20 0.37
CYP19A1 P11511 5/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
TBXA2R P21731 1/20 0.35
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965469 1.00 ALDH1A1 (0.40) ALDH1A1MAPTTBXAS1CYP19A1CA12
SCHEMBL7666696 0.93 ALDH1A1 (0.39) ALDH1A1MAPTTBXAS1CYP19A1CTNNB1
SCHEMBL7666704 0.93 ALDH1A1 (0.39) ALDH1A1MAPTTBXAS1CYP19A1CTNNB1
SCHEMBL7666712 0.93 ALDH1A1 (0.39) ALDH1A1MAPTTBXAS1CYP19A1CTNNB1
SCHEMBL6950461 0.73 RARG (0.44) ALDH1A1TBXAS1CYP19A1ESR1
SCHEMBL6950456 0.73 RARG (0.44) ALDH1A1TBXAS1CYP19A1ESR1
SCHEMBL6950464 0.73 RARG (0.44) ALDH1A1TBXAS1CYP19A1ESR1
SCHEMBL11369391 0.73 ALPG (0.63) CYP19A1CA12CA1CA2CA3
SCHEMBL6956897 0.72 CYP19A1 (0.51) TBXAS1CYP19A1
SCHEMBL6956907 0.72 CYP19A1 (0.51) TBXAS1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974584-B1 FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-01-15 EP disclosed