Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 19/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971564 | 0.90 | AVPR2 (0.54) | AVPR2AVPR1AOXTRNPSR1 | |
| SCHEMBL6964067 | 0.88 | AVPR2 (0.47) | AVPR2AVPR1AOXTR | |
| SCHEMBL6968495 | 0.84 | AVPR2 (0.54) | AVPR2AVPR1AOXTR | |
| SCHEMBL6963025 | 0.83 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL6965490 | 0.82 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL6958676 | 0.79 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL6969840 | 0.78 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL6964270 | 0.78 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL7087152 | 0.76 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL6969201 | 0.76 | AVPR2 (0.52) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |