Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965609 | 0.90 | AVPR2 (0.48) | AVPR2AVPR1AOXTRNPSR1 | |
| SCHEMBL6964067 | 0.85 | AVPR2 (0.47) | AVPR2AVPR1AOXTR | |
| SCHEMBL6971296 | 0.84 | AVPR2 (0.65) | AVPR2AVPR1AOXTR | |
| SCHEMBL6972433 | 0.83 | AVPR2 (0.54) | AVPR2ALDH1A1AVPR1AOXTR | |
| SCHEMBL6969981 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL6973411 | 0.79 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL6970545 | 0.79 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL6973134 | 0.79 | NPSR1 (0.47) | ALDH1A1GAANPSR1LMNA | |
| SCHEMBL6964828 | 0.78 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL6963125 | 0.78 | AVPR2 (0.69) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |