Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 12/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882898 | 0.83 | GSK3B (0.50) | TRPA1GSK3BENPP2CNR1TSHR | |
| SCHEMBL11615116 | 0.83 | GSK3B (0.50) | TRPA1GSK3BENPP2CNR1TSHR | |
| SCHEMBL2058684 | 0.80 | GSK3B (0.47) | GSK3BENPP2CNR1CNR2 | |
| SCHEMBL27948985 | 0.80 | GSK3B (0.51) | TRPA1GSK3BENPP2TSHRCLK4 | |
| SCHEMBL7353222 | 0.80 | GSK3B (0.47) | TRPA1GSK3BENPP2CNR1TSHR | |
| SCHEMBL30583585 | 0.80 | GSK3B (0.47) | GSK3BENPP2CNR1CNR2 | |
| SCHEMBL4083138 | 0.79 | ENPP2 (0.47) | GSK3BENPP2TSHRCLK4TNF | |
| SCHEMBL7307662 | 0.78 | TSHR (0.48) | TRPA1GSK3BENPP2CNR1TSHR | |
| SCHEMBL30961612 | 0.78 | TSHR (0.48) | TRPA1GSK3BENPP2CNR1TSHR | |
| SCHEMBL1500561 | 0.77 | GSK3B (0.45) | TRPA1GSK3BENPP2CNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |