Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26258579 | 0.85 | KDR (0.70) | NPC1RAB9AHTTSMN1; SMN2KDR | |
| SCHEMBL9867050 | 0.83 | RAB9A (1.00) | NPC1RAB9AHTTSMN1; SMN2KDR | |
| SCHEMBL7263545 | 0.82 | SMN1; SMN2 (1.00) | NPC1RAB9AHTTSMN1; SMN2KMT2A | |
| SCHEMBL28439885 | 0.82 | KDR (1.00) | NPC1RAB9AHTTKDRKMT2A | |
| SCHEMBL30117873 | 0.81 | RAB9A (0.79) | NPC1RAB9AHTTSMN1; SMN2KDR | |
| SCHEMBL3096372 | 0.81 | RAB9A (0.79) | NPC1RAB9AHTTSMN1; SMN2KDR | |
| SCHEMBL7372444 | 0.80 | NPC1 (0.71) | NPC1RAB9AKDRKMT2AMEN1 | |
| SCHEMBL14542182 | 0.80 | RAB9A (0.78) | NPC1RAB9AHTTSMN1; SMN2KDR | |
| SCHEMBL21616930 | 0.80 | KDR (0.63) | NPC1RAB9ASMN1; SMN2KDRKMT2A | |
| SCHEMBL1520680 | 0.80 | RAB9A (0.77) | NPC1RAB9AHTTSMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |