Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883004 | 0.85 | HCAR2 (0.56) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL11461421 | 0.85 | HCAR2 (0.56) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL9231000 | 0.83 | HCAR2 (0.54) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL538486 | 0.83 | HCAR2 (0.54) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL27774184 | 0.83 | HCAR2 (0.54) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL27701745 | 0.83 | HCAR2 (0.54) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL28472584 | 0.81 | HCAR2 (0.53) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL29016877 | 0.81 | HCAR2 (0.53) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL1054349 | 0.81 | HCAR2 (0.53) | HCAR2KDM4EMAPTTSHRLPAR1 | |
| SCHEMBL1766149 | 0.81 | HCAR2 (0.53) | HCAR2KDM4EMAPTTSHRLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |