SCHEMBL538486

SCHEMBL538486

CCC(=O)OC(C)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.54
KDM4E B2RXH2 2/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.46
LPAR1 Q92633 1/20 0.44
FFAR1 O14842 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LTB4R Q15722 2/20 0.42
LTB4R2 Q9NPC1 2/20 0.42
TP53 P04637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ELANE P08246 1/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
OPRM1 P35372 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231000 1.00 HCAR2 (0.54) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL27561241 0.96 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1
Alcohol SCHEMBL28805173 0.96 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL28249424 0.92 HCAR2 (0.47) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL3883004 0.86 HCAR2 (0.56) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL11461421 0.86 HCAR2 (0.56) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL27425819 0.85 RXRA (0.48) HCAR2MAPT
SCHEMBL6242067 0.85 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL5693685 0.85 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL585143 0.85 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
EP-4602141-A1 A FRAGRANCE MIXTURE (VI) Symrise AG (DE) 2025-08-20 EP claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
WO-2025056452-A1 PROCESS TO PRODUCE MATERIALS UNILEVER IP HOLDINGS B.V. (NL) 2025-03-20 WO claimed
EP-4519403-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-03-12 EP claimed
EP-4096618-B1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2025-01-29 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 US claimed
CN-1520846-A Quick-effective aerosol with plant aroma and its preparation 丛繁滋 2004-08-18 CN claimed
CN-1500477-A Quick result aerosol with plant aroma and its preparation 丛繁滋 2004-06-02 CN claimed
CN-1475204-A Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method 丛繁滋 2004-02-18 CN claimed
US-20030194454-A1 Pesticidal compositions containing rosemary oil and wintergreen oil ECOSMART TECHNOLOGIES, INC. 2003-10-16 US claimed
US-20030175369-A1 Natural moths repellent compositions PARAGON HOUSEHOLD PRODUCTS INC. 2003-09-18 US claimed
US-6534099-B1 Mixture also containing phenethyl proprionate and eugenol ECOSMART TECHNOLOGIES, INC. 2003-03-18 US claimed
US-6506707-B1 A synergistic blend of, eugenol and 2- phenethyl propionate ECOSMART TECHNOLOGIES, INC. 2003-01-14 US claimed
WO-2001091556-A2 PESTICIDAL COMPOSITIONS CONTAINING MENTHYL SALICYLATE ECOSMART TECHNOLOGIES, INC. (US) 2001-12-06 WO claimed
CN-1100331-A Multi-function, long-acting antiscolic disinfectant and its preparing method ZHENG S ELECTROCHEMISTRY SERVI (CN) 1995-03-22 CN claimed
US-5089162-A Liquid or grains, lemon scent, yellow color; automatic dishwasher detergent LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-02-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A HCAR2 3027/4885KDM4E 158/4885MAPT 4101/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 HCAR2 4372/4885KDM4E 1489/4885MAPT 689/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 HCAR2 3217/4885KDM4E 2903/4885MAPT 3311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.