Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.66 |
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.60 |
| ▸ | P4HB | P07237 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966141 | 1.00 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1P4HB | |
| SCHEMBL6954787 | 0.93 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6954791 | 0.93 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9827686 | 0.92 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9827681 | 0.92 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6967958 | 0.86 | CYSLTR2 (0.85) | CYSLTR1CYSLTR2 | |
| SCHEMBL6967961 | 0.86 | CYSLTR2 (0.85) | CYSLTR1CYSLTR2 | |
| SCHEMBL9828157 | 0.84 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL30383726 | 0.84 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9828739 | 0.84 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |