Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.54 |
| ▸ | MMP3 | P08254 | 9/20 | 0.54 |
| ▸ | MMP9 | P14780 | 6/20 | 0.54 |
| ▸ | MMP14 | P50281 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 10/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966390 | 1.00 | MMP2 (0.54) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6434243 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6434246 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL7205186 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6433679 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6433156 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6437467 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6437343 | 0.91 | MMP2 (0.50) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6434151 | 0.91 | MMP2 (0.50) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6587889 | 0.90 | MMP2 (0.65) | MMP2MMP3MMP9MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |