Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 4/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587638 | 1.00 | FDPS (0.73) | FDPSMAOBACHEBCHEHDAC1 | |
| SCHEMBL4813818 | 0.95 | FDPS (0.69) | FDPSMAOBACHEBCHEHDAC1 | |
| SCHEMBL4813804 | 0.95 | FDPS (0.69) | FDPSMAOBACHEBCHEHDAC1 | |
| SCHEMBL28859349 | 0.89 | FDPS (0.84) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL28859350 | 0.89 | FDPS (0.84) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL31087309 | 0.89 | FDPS (0.84) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL8046251 | 0.89 | FDPS (0.84) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL8046247 | 0.89 | FDPS (0.84) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL18010153 | 0.88 | FDPS (0.67) | FDPSMAOBACHEBCHEHDAC1 | |
| SCHEMBL16692743 | 0.88 | FDPS (0.67) | FDPSMAOBACHEBCHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679103-B2 | Multi-targeting agents for Alzheimer's disease therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-20 | — | — | US | disclosed |
| US-20200171016-A1 | MULTI-TARGETING AGENTS FOR ALZHEIMER'S DISEASE THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-04 | — | — | US | disclosed |
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200171016-A1 | MULTI-TARGETING AGENTS FOR ALZHEIMER'S DISEASE THERAPY | PSEN2, BACE2, APP | FDPS 4324/4885MAOB 1330/4885ACHE 270/4885 |
| US-11679103-B2 | Multi-targeting agents for Alzheimer's disease therapy | BACE2, PSEN2, APP | FDPS 4294/4885MAOB 1320/4885ACHE 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.