Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797334 | 0.84 | ALDH1A1 (0.64) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL6966315 | 0.84 | ALDH1A1 (0.69) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL76489 | 0.83 | ALDH1A1 (0.67) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL3077377 | 0.82 | ALDH1A1 (0.67) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL6967765 | 0.81 | ALDH1A1 (0.59) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL10547949 | 0.81 | ALDH1A1 (0.59) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| Hydrochloric Acid SCHEMBL27693713 | 0.80 | ALDH1A1 (0.64) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL13645595 | 0.80 | ALDH1A1 (0.65) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL94809 | 0.80 | ALDH1A1 (1.00) | ALDH1A1EPHX1KDM4EGAAMEN1 | |
| SCHEMBL6738230 | 0.80 | ALDH1A1 (0.64) | ALDH1A1EPHX1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |