⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514000 | 1.00 | — | — | |
| SCHEMBL3133477 | 0.79 | — | — | |
| SCHEMBL8593167 | 0.77 | ESR2 (0.62) | — | |
| SCHEMBL8337554 | 0.75 | CYP2A6 (0.46) | — | |
| SCHEMBL8289896 | 0.75 | CYP2A6 (0.46) | — | |
| SCHEMBL330857 | 0.75 | — | — | |
| SCHEMBL29767277 | 0.75 | — | — | |
| SCHEMBL31556280 | 0.75 | — | — | |
| SCHEMBL91997 | 0.75 | — | — | |
| SCHEMBL29497656 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509462-B2 | 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives | BioVersys AG (CH) | 2025-12-30 | — | — | US | disclosed |
| EP-3887375-B1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2024-11-20 | — | — | EP | disclosed |
| US-11945790-B2 | Compounds and methods for treating autoimmune disorders by targeting HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2022140464-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. | 2022-06-30 | — | — | US | disclosed |
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. | 2022-06-30 | — | — | US | disclosed |
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2022-01-27 | — | — | US | disclosed |
| EP-3887375-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | Bioversys AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| CN-108102103-B | Preparation method and application of micromolecular phosphate additive | 江苏苏博特新材料股份有限公司 | 2020-12-29 | — | — | CN | disclosed |
| WO-2020109350-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2020-06-04 | — | — | WO | disclosed |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004037176-A2 | QUINAZOLINONES AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004031145-A2 | LACTAM-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6333341-B1 | TUMOR NECROSIS FACTOR, ANTIINFLAMMATORY AGENTS AND ANALGESICS | AMGEN INC. | 2001-12-25 | — | — | US | disclosed |
| EP-0203827-B1 | PROCESS FOR PREPARING ORTHO-(ALKYLTHIO) PHENOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0203827-A1 | Process for preparing ortho-(alkylthio) phenols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4599451-A | PHENOL WITH DIALKYL DISULFIDE, ZIRCONIUM PHENOXIDE CATALYST | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4113939-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4058392-A | Tetrasubstituted urea compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |