Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.44 |
| ▸ | PLG | P00747 | 11/20 | 0.44 |
| ▸ | PLAT | P00750 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6433179 | 0.93 | PLAU (0.46) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6437275 | 0.85 | PLAU (0.47) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6435550 | 0.85 | PLAU (0.47) | PLAUPLGPLAT | |
| Trifluoroacetic Acid SCHEMBL6437930 | 0.83 | PLAU (0.64) | PLAUPLGPLAT | |
| Trifluoroacetic Acid SCHEMBL6434310 | 0.83 | PLAU (0.63) | PLAUPLGPLAT | |
| Trifluoroacetic Acid SCHEMBL7372419 | 0.82 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL6437934 | 0.80 | PLAU (0.53) | PLAUPLGPLAT | |
| Trifluoroacetic Acid SCHEMBL6434729 | 0.79 | PLAU (0.62) | PLAUPLGPLAT | |
| SCHEMBL6434317 | 0.79 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL6437441 | 0.78 | PLAU (0.57) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199440-A1 | Composition for the treatment of damaged tissue | PFIZER INC. | 2003-10-23 | — | — | US | disclosed |
| EP-1077945-B1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER (US) | 2003-01-08 | — | — | EP | disclosed |
| US-6093731-A | Isoquinolines | PFIZER INC. | 2000-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199440-A1 | Composition for the treatment of damaged tissue | MMP1, SERPINE1, COL14A1 | PLAU 119/4885PLG 33/4885PLAT 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.