Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912017 | 0.90 | DRD2 (0.64) | DRD2DRD4L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL21712168 | 0.90 | DRD2 (0.64) | DRD2DRD4L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8134006 | 0.87 | DRD2 (0.58) | DRD2DRD4L3MBTL1TSHRMAPT | |
| SCHEMBL30911988 | 0.84 | DRD2 (0.55) | DRD2DRD4L3MBTL1TSHRMAPT | |
| SCHEMBL30911996 | 0.84 | DRD2 (0.55) | DRD2DRD4L3MBTL1TSHRMAPT | |
| SCHEMBL30911989 | 0.84 | DRD2 (0.55) | DRD2DRD4L3MBTL1TSHRMAPT | |
| SCHEMBL30911973 | 0.84 | DRD2 (0.55) | DRD2DRD4L3MBTL1TSHRMAPT | |
| SCHEMBL27872558 | 0.82 | DRD2 (0.57) | DRD2DRD4L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL4425962 | 0.82 | MAPT (0.57) | DRD2DRD4L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL29876823 | 0.82 | MAPT (0.57) | DRD2DRD4L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1172809-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 1998-02-11 | — | — | CN | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |