Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6970396 | 0.91 | F2 (0.55) | F2NTRK1NTRK2ALDH1A1PKM | |
| SCHEMBL7673173 | 0.89 | F2 (0.46) | F2ALDH1A1PKMMEN1RECQL | |
| SCHEMBL6972029 | 0.87 | F2 (0.40) | F2NTRK1NTRK2ALDH1A1PKM | |
| SCHEMBL6974208 | 0.86 | BMP1 (0.45) | F2ALDH1A1PKMBMP1 | |
| SCHEMBL7664504 | 0.83 | F2 (0.43) | F2ALDH1A1THRBRECQLHDAC1 | |
| SCHEMBL6983757 | 0.83 | F2 (0.63) | F2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL6974949 | 0.82 | F2 (0.55) | F2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL6966635 | 0.82 | F2 (0.55) | F2ALDH1A1PKMGAA | |
| SCHEMBL7667173 | 0.82 | F2 (0.56) | F2ALDH1A1PKMMEN1RECQL | |
| SCHEMBL7664507 | 0.82 | HDAC1 (0.46) | F2ALDH1A1THRBRECQLHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220845-B1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-08-13 | — | — | EP | disclosed |
| EP-1220845-A1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-07-10 | — | — | EP | disclosed |
| US-6413990-B1 | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |
| WO-2001023359-A1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-04-05 | — | — | WO | disclosed |