⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746623 | 0.78 | — | — | |
| SCHEMBL13184212 | 0.73 | NR2F2 (0.49) | — | |
| SCHEMBL8447646 | 0.68 | MAPT (0.35) | — | |
| SCHEMBL20786209 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL22637764 | 0.68 | MAPT (0.53) | — | |
| SCHEMBL22637766 | 0.68 | MAPT (0.53) | — | |
| SCHEMBL22637738 | 0.66 | MAPT (0.60) | — | |
| SCHEMBL22637901 | 0.66 | MAPT (0.70) | — | |
| SCHEMBL22637863 | 0.66 | MAPT (0.75) | — | |
| SCHEMBL22637736 | 0.66 | MAPT (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283642-B1 | PROGNOSTIC BIOMARKERS FOR TTK INHIBITOR CHEMOTHERAPY | NETHERLANDS TRANSLATIONAL RES CENTER HOLDING B V (NL) | 2023-10-11 | — | — | EP | disclosed |
| US-10662193-B2 | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins | AC IMMUNE SA (CH) | 2020-05-26 | — | — | US | disclosed |
| US-10357477-B2 | Anticancer compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180071258-A1 | ANTICANCER COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-15 | — | — | US | disclosed |
| CN-107325262-A | Blocked isocyanate, coating composition, adhesive composite and article | 三井化学株式会社 | 2017-11-07 | — | — | CN | disclosed |
| CN-104797350-B | Method for forming multilayer coating film | 关西涂料株式会社 | 2017-09-15 | — | — | CN | disclosed |
| CN-107001854-A | Coating composition and coating prepared therefrom and application thereof | 巴斯夫涂料有限公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2016166255-A1 | PROGNOSTIC BIOMARKERS FOR TTK INHIBITOR CHEMOTHERAPY | NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V. (NL) | 2016-10-20 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |