Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967196 | 0.68 | — | — | |
| SCHEMBL22637918 | 0.64 | MAPT (0.61) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL22637920 | 0.64 | MAPT (0.61) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL1774571 | 0.63 | HTT (0.51) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL4684107 | 0.60 | DAO (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL20746623 | 0.59 | — | — | |
| SCHEMBL9357304 | 0.57 | PKM (0.44) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL9353447 | 0.57 | TDP1 (0.39) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL5200898 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL20702180 | 0.56 | HTT (0.47) | MAPTSMN1; SMN2ALDH1A1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701550-B1 | PROCESS FOR THE PRODUCTION OF AMINOALKYLGUANIDINES | ASTRA AB (SE) | 1999-03-31 | — | — | EP | disclosed |
| US-5659071-A | Process for the production of aminoalkylguanidines | ASTRA AKTIEBOLAG (SE) | 1997-08-19 | — | — | US | disclosed |
| EP-0701550-A1 | PROCESS FOR THE PRODUCTION OF AMINOALKYLGUANIDINES | Astra Aktiebolag (SE) | 1996-03-20 | — | — | EP | disclosed |
| US-5498724-A | Pyrazoleamidine compounds | AKTIEBOLAGET ASTRA (SE) | 1996-03-12 | — | — | US | disclosed |
| WO-1994029269-A1 | PROCESS FOR THE PRODUCTION OF AMINOALKYLGUANIDINES | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |