Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977516 | 0.91 | PGR (0.58) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6979646 | 0.88 | TSHR (0.52) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6979105 | 0.85 | CYP1A2 (0.52) | TSHRGAAKMT2AQPCT | |
| SCHEMBL6978590 | 0.85 | QPCT (0.49) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6980841 | 0.85 | CYP1A2 (0.51) | TSHRGAAKMT2AQPCT | |
| SCHEMBL6976593 | 0.85 | TSHR (0.49) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6981436 | 0.85 | CYP1A2 (0.51) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6980755 | 0.85 | TSHR (0.54) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6979128 | 0.85 | KMT2A (0.51) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6981540 | 0.85 | TSHR (0.47) | TSHRGAAKMT2AQPCTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |