Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966956 | 0.84 | CNR2 (0.42) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6979571 | 0.84 | CNR2 (0.56) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6967955 | 0.79 | CNR2 (0.61) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6972205 | 0.79 | MAPT (0.56) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6973326 | 0.78 | CNR2 (0.58) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6969393 | 0.76 | CNR2 (0.64) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6969154 | 0.76 | CNR2 (0.54) | PLA2G2ACNR2ACHECNR1MAPT | |
| Hydrochloric Acid SCHEMBL6971824 | 0.76 | CNR2 (0.63) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6978241 | 0.75 | CNR2 (0.49) | PLA2G2ACNR2ACHECNR1MAPT | |
| SCHEMBL6975679 | 0.75 | CNR2 (0.49) | PLA2G2ACNR2ACHECNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |