Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.49 |
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973326 | 0.89 | CNR2 (0.58) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6978241 | 0.89 | CNR2 (0.49) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6979571 | 0.86 | CNR2 (0.56) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6969154 | 0.83 | CNR2 (0.54) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6971235 | 0.79 | CNR2 (0.47) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6969393 | 0.78 | CNR2 (0.64) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6971046 | 0.78 | CNR1 (0.45) | CNR2ACHECNR1PLA2G2APTGER4 | |
| SCHEMBL6967955 | 0.78 | CNR2 (0.61) | CNR2ACHECNR1PLA2G2AMAPT | |
| Hydrochloric Acid SCHEMBL6971824 | 0.78 | CNR2 (0.63) | CNR2ACHECNR1PLA2G2AMAPT | |
| SCHEMBL6972205 | 0.77 | MAPT (0.56) | CNR2ACHECNR1PLA2G2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |