Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NPR3 | P17342 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967718 | 1.00 | PABPC1 (0.41) | PABPC1SCN9AP2RX7EPHX2HDAC8 | |
| SCHEMBL6965676 | 0.95 | PABPC1 (0.41) | PABPC1SCN9AP2RX7EPHX2HDAC8 | |
| SCHEMBL6965678 | 0.95 | PABPC1 (0.41) | PABPC1SCN9AP2RX7EPHX2HDAC8 | |
| SCHEMBL6957710 | 0.93 | KLK7 (0.40) | PABPC1SCN9AP2RX7CTSS | |
| SCHEMBL6957715 | 0.93 | KLK7 (0.40) | PABPC1SCN9AP2RX7CTSS | |
| SCHEMBL6966152 | 0.91 | KLK7 (0.34) | PABPC1SCN9AP2RX7HDAC8NPR3 | |
| SCHEMBL6956720 | 0.91 | SCN9A (0.33) | PABPC1SCN9A | |
| SCHEMBL6957720 | 0.91 | SCN9A (0.35) | PABPC1SCN9A | |
| SCHEMBL6961693 | 0.90 | SCN9A (0.38) | PABPC1SCN9ANPR3 | |
| SCHEMBL6961689 | 0.90 | SCN9A (0.38) | PABPC1SCN9ANPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |