Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221137 | 0.82 | NAMPT (0.61) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL7217481 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL11366279 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL31475190 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL29583694 | 0.81 | GAA (0.62) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL31148337 | 0.81 | HDAC1 (0.61) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL30046370 | 0.79 | HDAC1 (0.69) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL405785 | 0.79 | HDAC1 (0.69) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL2222999 | 0.79 | HDAC1 (0.69) | HDAC1HDAC6HPGDGAACES2 | |
| SCHEMBL1116683 | 0.79 | HDAC1 (0.59) | HDAC1HDAC6HPGDGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |