Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.57 |
| ▸ | MMP13 | P45452 | 17/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MMP10 | P09238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960996 | 0.95 | MMP1 (0.60) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL6947434 | 0.90 | MMP1 (0.69) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL7208085 | 0.88 | MMP1 (0.68) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL6957161 | 0.88 | MMP1 (0.67) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6965530 | 0.86 | MMP1 (0.67) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7214305 | 0.85 | MMP1 (0.67) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL6968323 | 0.85 | MMP1 (0.68) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6967193 | 0.83 | MMP1 (0.66) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6957079 | 0.81 | MMP1 (0.80) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6954028 | 0.79 | MMP1 (0.69) | MMP1MMP13MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977733-B1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-09-03 | — | — | EP | claimed |