Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974802 | 0.97 | NPSR1 (0.55) | NPSR1LMNAHSD17B10MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL6970908 | 0.85 | LMNA (0.59) | NPSR1LMNAHSD17B10MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6974987 | 0.83 | LMNA (0.59) | NPSR1LMNAHSD17B10MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6969439 | 0.83 | LMNA (0.59) | NPSR1LMNAHSD17B10MAPK1KDM4E | |
| Fumaric Acid SCHEMBL6960310 | 0.82 | LMNA (0.55) | NPSR1LMNAHSD17B10MAPK1ALDH1A1 | |
| Maleic Acid SCHEMBL6960299 | 0.82 | LMNA (0.55) | NPSR1LMNAHSD17B10MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6966809 | 0.80 | NPSR1 (0.66) | NPSR1LMNAHSD17B10MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL6967294 | 0.80 | NPSR1 (0.66) | NPSR1LMNAHSD17B10MAPK1KDM4E | |
| Maleic Acid SCHEMBL6969690 | 0.78 | LMNA (0.53) | NPSR1LMNAHSD17B10MAPK1KDM4E | |
| Fumaric Acid SCHEMBL6969703 | 0.78 | LMNA (0.53) | NPSR1LMNAHSD17B10MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |