SCHEMBL6967997

SCHEMBL6967997

O=C1CCOc2c1cccc2C1CCN([C@@H]2Cc3cc(F)ccc3[C@H]2O)CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 19/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6968003 1.00 HTR1A (0.77) HTR1A
SCHEMBL6973930 0.87 HTR1A (1.00) HTR1A
SCHEMBL6973936 0.87 HTR1A (1.00) HTR1A
SCHEMBL6972601 0.83 HTR1A (1.00) HTR1A
SCHEMBL6972605 0.83 HTR1A (1.00) HTR1A
SCHEMBL6976540 0.83 HTR1A (0.78) HTR1A
SCHEMBL6964810 0.83 HTR1A (1.00) HTR1A
SCHEMBL6964807 0.83 HTR1A (1.00) HTR1A
SCHEMBL6974672 0.83 HTR1A (1.00) HTR1A
SCHEMBL6976537 0.83 HTR1A (0.78) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906912-B1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-01-08 EP claimed
US-6060487-A Indanol compounds ADIR ET COMPAGNIE (FR) 2000-05-09 US claimed
EP-0906912-A1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-04-07 EP claimed
US-6060487-A Indanol compounds ADIR ET COMPAGNIE (FR) 2000-05-09 US disclosed
US-5958927-A PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS ADIR ET COMPAGNIE (FR) 1999-09-28 US disclosed