Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | KIT | P10721 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968471 | 1.00 | PTGS2 (0.68) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6965970 | 0.91 | MAOB (0.81) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6970250 | 0.91 | MAOB (0.81) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6964657 | 0.90 | MAOB (0.66) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6964652 | 0.90 | MAOB (0.66) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6963130 | 0.87 | MEN1 (0.71) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6963133 | 0.87 | MEN1 (0.71) | PTGS2MAOBKITKDM4ERAB9A | |
| SCHEMBL6969954 | 0.85 | MEN1 (0.70) | PTGS2MAOBKDM4ERAB9AMEN1 | |
| SCHEMBL6969956 | 0.85 | MEN1 (0.70) | PTGS2MAOBKDM4ERAB9AMEN1 | |
| SCHEMBL6956102 | 0.84 | PTGS2 (0.66) | PTGS2MAOBKITKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |