Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.56 |
| ▸ | CTSL | P07711 | 9/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.39 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | LONP1 | P36776 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.39 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106073 | 0.88 | CTSS (0.58) | CTSSCTSLCTSBCTSKPSMB11 | |
| SCHEMBL6969181 | 0.86 | CTSS (0.43) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL6974066 | 0.86 | CTSS (0.61) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5366893 | 0.85 | CTSS (0.62) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6973028 | 0.84 | CTSS (0.57) | CTSSCTSLCTSBCTSKPSMB11 | |
| SCHEMBL6964214 | 0.83 | CTSS (0.68) | CTSSCTSLCTSB | |
| SCHEMBL5365007 | 0.82 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5364122 | 0.82 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6109621 | 0.82 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6107308 | 0.81 | CTSS (0.65) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |