Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976739 | 0.91 | MTNR1A (0.46) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL8132268 | 0.89 | CCR8 (0.49) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6963986 | 0.89 | CCR8 (0.49) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6868973 | 0.89 | CCR8 (0.49) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL8127943 | 0.86 | CCR8 (0.48) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6964191 | 0.86 | CCR8 (0.48) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6970611 | 0.86 | CCR8 (0.48) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL7081016 | 0.86 | CCR8 (0.48) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6968981 | 0.85 | CCR8 (0.48) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 | |
| SCHEMBL6966222 | 0.85 | CCR8 (0.49) | CCR8MTNR1AMTNR1BSLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |