Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 8/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080662 | 0.95 | LMNA (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL7084576 | 0.90 | LMNA (0.35) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL6964484 | 0.90 | CACNA1F (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL7080305 | 0.89 | LMNA (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL6971525 | 0.86 | NPC1 (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL6972247 | 0.86 | HSP90AA1 (0.38) | LMNACYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL6969465 | 0.85 | MAOB (0.38) | LMNAMEN1KMT2A | |
| SCHEMBL7084556 | 0.85 | EPHX1 (0.34) | LMNACYP2C9CYP2C19MEN1CYP1A2 | |
| SCHEMBL6973302 | 0.85 | MEN1 (0.35) | LMNACYP2C9CYP2C19MEN1CYP1A2 | |
| SCHEMBL6961350 | 0.85 | LMNA (0.43) | LMNACYP2C9CYP2C19MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |