Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 7/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965959 | 0.98 | TSHR (0.40) | ALDH1A1TSHRCYP3A4NAAAHPGD | |
| SCHEMBL6965324 | 0.93 | — | — | |
| SCHEMBL6958279 | 0.86 | — | — | |
| SCHEMBL6076862 | 0.79 | — | — | |
| SCHEMBL133539 | 0.78 | — | — | |
| SCHEMBL19242300 | 0.77 | CHRM2 (0.41) | ALDH1A1TSHRNAAA | |
| SCHEMBL2688058 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4NAAAEPHX1 | |
| SCHEMBL5397748 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4NAAAEPHX1 | |
| SCHEMBL7841371 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4NAAAEPHX1 | |
| SCHEMBL10887363 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |