Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26431397 | 0.98 | SIGMAR1 (0.96) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| SCHEMBL6975263 | 0.98 | SIGMAR1 (0.96) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| SCHEMBL8092983 | 0.96 | SIGMAR1 (1.00) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| Hydrochloric Acid SCHEMBL9718246 | 0.96 | SIGMAR1 (0.92) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| SCHEMBL19631563 | 0.93 | SIGMAR1 (0.88) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| SCHEMBL22697176 | 0.93 | SIGMAR1 (0.88) | SIGMAR1CYP1A2MAPTEPHX1TNKS2 | |
| SCHEMBL1858791 | 0.93 | SIGMAR1 (0.79) | SIGMAR1CYP1A2MAPTEPHX1 | |
| SCHEMBL27368119 | 0.91 | SIGMAR1 (0.83) | SIGMAR1CYP1A2MAPTEPHX1 | |
| SCHEMBL1859093 | 0.91 | SIGMAR1 (0.83) | SIGMAR1CYP1A2MAPTEPHX1 | |
| SCHEMBL6962219 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900672-B1 | BET-PROTEIN INHIBITORY 5-ARYL-TRIAZOLO-AZEPINES | Bayer Pharma AG (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |