Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.31 |
| ▸ | SPR | P35270 | 3/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991378 | 0.91 | AXL (0.35) | PFKFB3ALDH1A1 | |
| SCHEMBL6997579 | 0.91 | AXL (0.35) | PFKFB3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6991405 | 0.90 | AXL (0.34) | PFKFB3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7159588 | 0.90 | POLB (0.36) | GRM5PFKFB3ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6993609 | 0.90 | AXL (0.34) | PFKFB3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6991842 | 0.90 | AXL (0.34) | PFKFB3ALDH1A1 | |
| SCHEMBL6956691 | 0.88 | PTK2 (0.40) | PIN1PFKFB3LRRK2 | |
| Revaprazan SCHEMBL6990999 | 0.84 | MEN1 (0.40) | PFKFB3TRPC3TRPC6ALDH1A1KMT2A | |
| Revaprazan SCHEMBL2194461 | 0.84 | MEN1 (0.40) | PFKFB3TRPC3TRPC6ALDH1A1KMT2A | |
| Revaprazan SCHEMBL6993033 | 0.84 | MEN1 (0.40) | PFKFB3TRPC3TRPC6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |