Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Revaprazan SCHEMBL29388090 | 1.00 | MEN1 (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL2194461 | 1.00 | MEN1 (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL6990999 | 1.00 | MEN1 (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL2687104 | 0.99 | LMNA (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL29405266 | 0.99 | LMNA (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL29407864 | 0.99 | LMNA (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL6994677 | 0.99 | LMNA (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL6992634 | 0.99 | LMNA (0.40) | MEN1BLMKMT2AHPGDKDM4E | |
| Revaprazan SCHEMBL1651435 | 0.98 | MEN1 (0.38) | MEN1BLMKMT2AHPGDKDM4E | |
| SCHEMBL6994315 | 0.92 | SMN1; SMN2 (0.40) | MEN1KMT2AHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |