Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332188 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL11332190 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6976986 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6976988 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6976996 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6969488 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6969479 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6965397 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3131663 | 0.74 | MAPT (0.54) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A | |
| SCHEMBL30810472 | 0.74 | MAPT (0.54) | ALDH1A1SOS1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |