Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL696967

Cc1ccc(N(C)C)cc1.N

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.94
TSHR P16473 5/20 0.94
ALOX15 P16050 3/20 0.69
HSD17B10 Q99714 2/20 0.69
MAPK1 P28482 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
CYP3A4 P08684 3/20 0.52
TP53 P04637 2/20 0.52
MAPT P10636 4/20 0.50
LMNA P02545 1/20 0.50
GFER P55789 1/20 0.50
MCL1 Q07820 1/20 0.50
ACHE P22303 1/20 0.50
KDM4E B2RXH2 3/20 0.48
GAA P10253 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SLC2A1 P11166 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20678561 0.97 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL28378 0.97 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL21065752 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
Bromide SCHEMBL20876003 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL15346028 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
Lithium Ion SCHEMBL19732784 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
Hydrochloric Acid SCHEMBL2861537 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL29910586 0.94 ALDH1A1 (0.94) ALDH1A1TSHRALOX15HSD17B10MAPK1
Methyl Alcohol SCHEMBL9500919 0.91 ALDH1A1 (0.88) ALDH1A1TSHRALOX15HSD17B10MAPK1
Fluoride Ion SCHEMBL3700549 0.91 ALDH1A1 (0.88) ALDH1A1TSHRALOX15HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4346744-A1 THIOL URETHANE GROUP-CONTAINING POLYMERIZABLE COMPOSITION Kulzer GmbH (DE) 2024-04-10 EP disclosed
CN-114573866-B Filler special for marble adhesive and preparation method thereof 江西广源化工有限责任公司 2024-02-02 CN disclosed
EP-3689290-B1 METHOD FOR PRODUCING A PARTIAL OR TOTAL PROSTHESIS, AND PROSTHESIS OBTAINABLE BY THIS METHOD KULZER & CO GMBH (DE) 2023-11-22 EP disclosed
US-11597735-B2 Highly efficient free radical photopolymerizations through enabled dark cure THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-03-07 US disclosed
CN-114573866-A Special filler for marble adhesive and preparation method thereof 江西广源化工有限责任公司 2022-06-03 CN disclosed
EP-3164097-B1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL KULZER & CO GMBH (DE) 2022-05-11 EP disclosed
US-20210163508-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2021-06-03 US disclosed
WO-2021083992-A1 DENTAL COMPOSITE MATERIAL KULZER GMBH (DE) 2021-05-06 WO disclosed
WO-2021083995-A1 POLYMERIZABLE COMPOSITION KULZER GMBH (DE) 2021-05-06 WO disclosed
EP-3689290-A2 METHOD FOR PRODUCING A PARTIAL OR TOTAL PROSTHESIS, AND PROSTHESIS OBTAINABLE BY THIS METHOD Kulzer GmbH (DE) 2020-08-05 EP disclosed
EP-2346539-B1 POLYMERIZABLE MULTI-COMPONENT PROSTHESIS STARTING MATERIAL, PARTICULARLY FOR DENTAL PROSTHESES RETEC KUNSTSTOFFTECHNIK GMBH (DE) 2013-01-02 EP disclosed
EP-2529762-A2 Prosthetic base material that is break-resistant after hardening, derived from autopolymerising or cold polymerising compounds Heraeus Kulzer GmbH (DE) 2012-12-05 EP disclosed
EP-2422824-A2 Basic prosthesis material, in particular for dental prosthetics Retec Kunststofftechnik GmbH (DE) 2012-02-29 EP disclosed
EP-2346539-A1 POLYMERIZABLE MULTI-COMPONENT PROSTHESIS STARTING MATERIAL, PARTICULARLY FOR DENTAL PROSTHESES Retec Kunststofftechnik GmbH (DE) 2011-07-27 EP disclosed
WO-2010051793-A1 POLYMERIZABLE MULTI-COMPONENT PROSTHESIS STARTING MATERIAL, PARTICULARLY FOR DENTAL PROSTHESES RETEC KUNSTSTOFFTECHNIK GMBH (DE) 2010-05-14 WO disclosed
EP-0802221-B1 Silica based filler, process for its production and use thereof HERAEUS KULZER GMBH (DE) 2006-06-07 EP disclosed
EP-0717976-B1 Polymerisable dental material HERAEUS KULZER GMBH & CO KG (DE) 2003-09-03 EP disclosed
US-6096842-A Aerobically curable adhesive HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-08-01 US disclosed
EP-0802221-A1 Silica based filler, process for its production and use thereof Heraeus Kulzer GmbH (DE) 1997-10-22 EP disclosed
EP-0717976-A2 Polymerisable dental material HERAEUS KULZER GMBH (DE) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11597735-B2 Highly efficient free radical photopolymerizations through enabled dark cure PHF2, KDM3B, KDM2B ALDH1A1 1321/4885TSHR 4673/4885ALOX15 923/4885
US-20210163508-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE PHF2, KDM3B, KDM2B ALDH1A1 1321/4885TSHR 4673/4885ALOX15 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.