Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.57 |
| ▸ | BCL6 | P41182 | 1/20 | 0.52 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954918 | 0.90 | MAPT (0.69) | MAPTKDM4EKAT2BBCL6BCOR | |
| SCHEMBL20529704 | 0.88 | MAPT (0.57) | MAPTKDM4EKAT2BBCL6BCOR | |
| SCHEMBL8120801 | 0.88 | MAPT (0.57) | MAPTKDM4EKAT2BBCL6BCOR | |
| SCHEMBL2309492 | 0.84 | MAPT (0.54) | MAPTKDM4EKAT2BBCL6BCOR | |
| SCHEMBL30697331 | 0.84 | KAT2B (0.63) | MAPTKAT2BBCL6BCORALDH1A1 | |
| SCHEMBL29126150 | 0.84 | KAT2B (0.63) | MAPTKAT2BBCL6BCORALDH1A1 | |
| SCHEMBL2314605 | 0.82 | MAPT (0.54) | MAPTKDM4EBCL6BCORALDH1A1 | |
| SCHEMBL4594932 | 0.81 | MAPT (0.50) | MAPTKDM4EBCL6BCORALDH1A1 | |
| SCHEMBL9831653 | 0.81 | NLRP3 (0.61) | MAPTKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL8191963 | 0.81 | MAPT (0.67) | MAPTKDM4EKAT2BBCL6BCOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |