SCHEMBL6970197

SCHEMBL6970197

OC1c2cc(F)c(F)cc2CC1N1CCC(c2cccc3c2OCCO3)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970190 1.00 HTR1A (1.00) HTR1A
SCHEMBL6974672 0.90 HTR1A (1.00) HTR1A
SCHEMBL6964810 0.90 HTR1A (1.00) HTR1A
SCHEMBL6964807 0.90 HTR1A (1.00) HTR1A
SCHEMBL6976151 0.89 HTR1A (1.00) HTR1A
SCHEMBL6976154 0.89 HTR1A (1.00) HTR1A
SCHEMBL6965937 0.88 HTR1A (1.00) HTR1A
SCHEMBL6975378 0.86 HTR1A (1.00) HTR1A
SCHEMBL6975371 0.86 HTR1A (1.00) HTR1A
SCHEMBL6969696 0.85 HTR1A (1.00) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906912-B1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-01-08 EP disclosed
US-6060487-A Indanol compounds ADIR ET COMPAGNIE (FR) 2000-05-09 US disclosed
CN-1218051-A New 2,3-dioxide, indanol compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-06-02 CN disclosed
EP-0906912-A1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-04-07 EP disclosed