Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.81 |
| ▸ | BRD4 | O60885 | 2/20 | 0.66 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948154 | 0.94 | MAPK14 (0.90) | MAPK14BRD4BRDT | |
| SCHEMBL6949712 | 0.91 | MAPK14 (0.85) | MAPK14BRD4BRDT | |
| SCHEMBL6946216 | 0.90 | MAPK14 (0.84) | MAPK14BRD4BRDT | |
| SCHEMBL6974464 | 0.90 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL4907707 | 0.90 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL4912070 | 0.89 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL6949268 | 0.87 | MAPK14 (0.81) | MAPK14BRD4BRDT | |
| SCHEMBL6949269 | 0.87 | MAPK14 (0.81) | MAPK14BRD4BRDT | |
| SCHEMBL4917866 | 0.87 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL4915267 | 0.86 | MAPK14 (0.80) | MAPK14BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900083-B1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-08-20 | — | — | EP | disclosed |
| US-5977103-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5864036-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |