Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979156 | 1.00 | IDO1 (0.37) | IDO1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL13970345 | 0.73 | IDO1 (0.47) | IDO1ALDH1A1HPGD | |
| SCHEMBL21678055 | 0.73 | CYP2D6 (0.49) | IDO1ALDH1A1LMNACYP2D6MAPK1 | |
| SCHEMBL23802727 | 0.72 | CYP2D6 (0.48) | IDO1ALDH1A1LMNACYP2D6MAPK1 | |
| SCHEMBL23802816 | 0.72 | CYP2D6 (0.48) | IDO1ALDH1A1LMNACYP2D6MAPK1 | |
| SCHEMBL23255157 | 0.70 | ALDH1A1 (0.48) | IDO1ALDH1A1 | |
| SCHEMBL18886185 | 0.70 | ALDH1A1 (0.48) | IDO1ALDH1A1 | |
| SCHEMBL23255515 | 0.70 | ALDH1A1 (0.48) | IDO1ALDH1A1 | |
| SCHEMBL6970498 | 0.70 | GLA (0.39) | ALDH1A1GLANPSR1SMN1; SMN2 | |
| SCHEMBL6967749 | 0.70 | GLA (0.39) | ALDH1A1GLANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |