⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270145 | 0.72 | — | — | |
| SCHEMBL8764204 | 0.67 | — | — | |
| SCHEMBL8764000 | 0.67 | — | — | |
| SCHEMBL8764156 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL1378116 | 0.59 | — | — | |
| SCHEMBL8764206 | 0.59 | ADH1B (0.39) | — | |
| SCHEMBL10401990 | 0.56 | — | — | |
| SCHEMBL1137160 | 0.56 | — | — | |
| SCHEMBL23961 | 0.50 | — | — | |
| SCHEMBL1686590 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083015-B1 | BIS-(FLUORO AND CHLOROMETHYL THIOFORMAMIDE), PREPARATION AND USE THEREOF | BAYER AG (DE) | 1984-11-07 | — | — | EP | claimed |
| EP-0083015-A1 | Bis-(fluoro and chloromethyl thioformamide), preparation and use thereof | BAYER AG (DE) | 1983-07-06 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-4532259-A | Protect industrial material against attack by fungi, bacteria, insects | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0083015-B1 | BIS-(FLUORO AND CHLOROMETHYL THIOFORMAMIDE), PREPARATION AND USE THEREOF | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0083015-B1 | BIS-(FLUORO AND CHLOROMETHYL THIOFORMAMIDE), PREPARATION AND USE THEREOF | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0083015-A1 | Bis-(fluoro and chloromethyl thioformamide), preparation and use thereof | BAYER AG (DE) | 1983-07-06 | — | — | EP | disclosed |
| EP-0083015-A1 | Bis-(fluoro and chloromethyl thioformamide), preparation and use thereof | BAYER AG (DE) | 1983-07-06 | — | — | EP | disclosed |
| EP-0083015-A1 | Bis-(fluoro and chloromethyl thioformamide), preparation and use thereof | BAYER AG (DE) | 1983-07-06 | — | — | EP | disclosed |