Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976577 | 0.98 | — | — | |
| SCHEMBL6982032 | 0.75 | TP53 (0.32) | — | |
| SCHEMBL6977440 | 0.71 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL6981416 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL23585075 | 0.68 | CYP2D6 (0.50) | MEN1MAPTKMT2A | |
| SCHEMBL10955098 | 0.68 | CYP2D6 (0.50) | MEN1MAPTKMT2A | |
| SCHEMBL25834098 | 0.68 | CYP2D6 (0.50) | MEN1MAPTKMT2A | |
| SCHEMBL11191021 | 0.68 | CYP2D6 (0.45) | MEN1MAPTKMT2A | |
| SCHEMBL23104905 | 0.67 | PLG (0.41) | MEN1MAPTKMT2AATM | |
| SCHEMBL6979078 | 0.67 | POLB (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |