Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | PPARA | Q07869 | 10/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970790 | 1.00 | FFAR1 (0.62) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL7161684 | 0.91 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL7161681 | 0.91 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL7161688 | 0.91 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL6955816 | 0.87 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL7162171 | 0.86 | FFAR1 (0.64) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL7162169 | 0.86 | FFAR1 (0.64) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6966725 | 0.84 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6966729 | 0.84 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6587331 | 0.84 | MAPT (0.49) | FFAR1PPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |