Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587340 | 1.00 | MAPT (0.49) | MAPTKDM4EALDH1A1FFAR1CA2 | |
| SCHEMBL6583466 | 0.89 | MAPT (0.47) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6583468 | 0.89 | MAPT (0.47) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6583243 | 0.88 | TRPA1 (0.48) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6583241 | 0.88 | TRPA1 (0.48) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6583665 | 0.88 | KDR (0.49) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6583671 | 0.88 | KDR (0.49) | MAPTKDM4EALDH1A1FFAR1APP | |
| SCHEMBL6157314 | 0.85 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1FFAR1KDR | |
| SCHEMBL6583866 | 0.84 | MAPT (0.48) | MAPTKDM4EALDH1A1FFAR1KDR | |
| SCHEMBL6970790 | 0.84 | FFAR1 (0.62) | MAPTKDM4EFFAR1KDRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |