Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RNF4 | P78317 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970837 | 0.77 | SMN1; SMN2 (0.40) | JAK2ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6968863 | 0.73 | — | — | |
| SCHEMBL6964684 | 0.73 | — | — | |
| SCHEMBL6958196 | 0.69 | — | — | |
| SCHEMBL965930 | 0.69 | — | — | |
| SCHEMBL6967334 | 0.67 | — | — | |
| SCHEMBL19534 | 0.67 | — | — | |
| SCHEMBL28860927 | 0.67 | — | — | |
| SCHEMBL11356010 | 0.67 | ALDH1A1 (0.39) | JAK2ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28827579 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |