Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979275 | 0.86 | SLC6A3 (0.71) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL113040 | 0.86 | SLC6A3 (0.71) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL30505635 | 0.86 | SLC6A3 (0.71) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL11309362 | 0.85 | SLC6A3 (0.69) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL8777320 | 0.85 | SLC6A3 (0.69) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL725404 | 0.83 | KMT2A (0.76) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1914132 | 0.83 | SLC6A3 (0.72) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL6948356 | 0.83 | SLC6A3 (0.72) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL11874477 | 0.83 | PRSS1 (0.68) | SLC6A3KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL28263594 | 0.83 | HSD17B10 (0.72) | SLC6A3KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |