Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730960 | 0.77 | EPHX1 (0.41) | EPHX1TSHRTET2SMN1; SMN2 | |
| SCHEMBL15033686 | 0.75 | EPHX1 (0.40) | EPHX1TSHRTET2 | |
| SCHEMBL15614667 | 0.73 | EPHX1 (0.39) | EPHX1TSHRTET2SMN1; SMN2 | |
| SCHEMBL14930633 | 0.73 | EPHX1 (0.39) | EPHX1TSHRTET2 | |
| SCHEMBL22680370 | 0.73 | EPHX1 (0.39) | EPHX1TSHRTET2 | |
| SCHEMBL7290046 | 0.72 | CYP2D6 (0.36) | — | |
| SCHEMBL28649387 | 0.71 | EPHX1 (0.38) | EPHX1TSHRTET2 | |
| SCHEMBL11622228 | 0.70 | EPHX1 (0.40) | EPHX1TSHRTET2SMN1; SMN2 | |
| SCHEMBL9089174 | 0.70 | EPHX1 (0.40) | EPHX1TSHRTET2SMN1; SMN2 | |
| SCHEMBL13037023 | 0.70 | KDM4E (0.40) | EPHX1TSHRTET2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |