Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027841 | 1.00 | LTB4R (0.68) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL17027837 | 1.00 | LTB4R (0.68) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL6344592 | 1.00 | LTB4R (0.68) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL7385392 | 0.98 | LTB4R (0.66) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL3254192 | 0.93 | LTB4R (0.59) | LTB4RMAPTRXFP1TSHRKMT2A | |
| SCHEMBL15587062 | 0.93 | LTB4R (0.59) | LTB4RMAPTRXFP1TSHRKMT2A | |
| SCHEMBL8826605 | 0.93 | LTB4R (0.59) | LTB4RMAPTRXFP1TSHRKMT2A | |
| SCHEMBL28012282 | 0.86 | LTB4R (0.58) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL11833507 | 0.86 | LTB4R (0.54) | LTB4RMAPTRXFP1TRPA1TSHR | |
| SCHEMBL11837264 | 0.86 | LTB4R (0.54) | LTB4RMAPTRXFP1TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324997-A2 | DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY | Shire Biochem Inc. (CA) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030922-A2 | DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY | SHIRE BIOCHEM INC. (CA) | 2002-04-18 | — | — | WO | disclosed |