Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287644 | 0.89 | HSD17B10 (0.68) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL8886874 | 0.87 | HSD17B10 (0.66) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL29315383 | 0.85 | HSD17B10 (0.64) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL30892502 | 0.82 | BRD4 (0.62) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL10822262 | 0.82 | BRD4 (0.62) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL6971901 | 0.81 | KDM4E (0.48) | HSD17B10POLBALDH1A1HPGDLMNA | |
| SCHEMBL30356246 | 0.81 | KMT2A (0.70) | BRD4POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL171580 | 0.81 | KMT2A (0.70) | BRD4POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10930815 | 0.81 | HSD17B10 (0.59) | HSD17B10BRD4POLBALDH1A1HPGD | |
| SCHEMBL27596581 | 0.81 | HSD17B10 (0.68) | HSD17B10BRD4POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |